51 chronicles what happens after political pressure from the American public forces the Air Force to provide a few well-known reporters with limited access to the most secretive base on the planet: Area 51. When one of the base's hidden 'long term visitors' exploits this unprecedented visit as a chance to liberate himself and his fellow alien captives, Area 51 turns from a secure government base to a horrifying destination of terror.

Paramilitary operative David Wolfe stumbles upon an international conspiracy connecting presidential cabinet members to a Middle Eastern terrorist plot. Wanting to expose the truth, Wolfe defies orders and returns to the US as an army of one fighting for American security and integrity.